Structural insights into chemokine CCL17 recognition by antibody M116
نویسندگان
چکیده
منابع مشابه
Structural insights into chemokine CCL17 recognition by antibody M116
The homeostatic chemokine CCL17, also known as thymus and activation regulated chemokine (TARC), has been associated with various diseases such as asthma, idiopathic pulmonary fibrosis, atopic dermatitis and ulcerative colitis. Neutralization of CCL17 by antibody treatment ameliorates the impact of disease by blocking influx of T cells. Monoclonal antibody M116 derived from a combinatorial libr...
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ژورنال
عنوان ژورنال: Biochemistry and Biophysics Reports
سال: 2018
ISSN: 2405-5808
DOI: 10.1016/j.bbrep.2017.11.005